Built in 1972 by architects Morin, Longwood & Edlund, the Horse Center is located on approximately 250 acres just two miles west of campus on Walnut Boulevard. The facilities include indoor and outdoor arenas, a 35-stall main barn, 7-stall staff barn, 5-stall research/foaling barn, turnout pastures and paddocks, hay fields, and a hay barn. Approximately 15 horses are owned by OSU, and other privately owned horses are boarded there by OSU students.

The OSU Horse Center offers classes in Introductory Horse Science, Stable Management, Equine Exercise Physiology, Colt Training, Equine Nutrition, and Equine Reproduction. Approximately 100 students take classes here annually, and a few hundred more participate in the classes that tour the Horse Center or utilize the facility for teaching.